About ThinkBIG®
Every year, children across central and northeast Pennsylvania face the heartbreaking reality of a pediatric cancer diagnosis. In 2014, Dr. Colby Wesner founded ThinkBIG® to bring comfort and support to these children and their families—an idea inspired by one very special patient.
Carmine’s Story
At just nine years old, Carmine Monacelli was diagnosed with a form of bone cancer. Despite undergoing rounds of chemotherapy and radiation, Carmine never let cancer take away his spirit. He dreamed big—one day envisioning himself as a marine biologist, the next as a professional wrestler. No matter the setbacks, his positivity and determination never wavered.
Dr. Wesner visited Carmine often during his treatments, and Carmine’s courage and optimism left a lasting mark. When Carmine passed away in March 2012, his legacy of “thinking big” became the driving force behind ThinkBIG®. Today, the fund continues in his honor, helping families who are navigating the challenges of pediatric cancer.
Why ThinkBIG?
While many organizations focus on funding cancer research, ThinkBIG® addresses another urgent need: the immediate financial hardships families face while caring for a child with cancer. From travel expenses to daily living costs, the burden can be overwhelming.
That’s where your generosity makes a difference. Every gift, no matter the size, directly supports families in need—providing hope, relief, and the reminder that they are not alone.
